Reperfusion therapy for acute coronary occlusion.
نویسندگان
چکیده
منابع مشابه
Reperfusion after Acute Coronary Occlusion in Dogs
Endothelial injury may contribute to the augmented coronary vascular tone seen in myocardial ischemia by impairing endothelial production or release of vasodilators. In vitro reactivity of arterial rings was studied after 60 min of coronary occlusion and 60 min of reperfusion in anesthetized dogs. Ischemia without reperfusion blunted contractile reactivity to potassium chloride (KCI), whereas i...
متن کاملElectrophysiologic Effects of Coronary Occlusion and Reperfusion
In order to determine the electrophysiological changes that occur during coronary occlusion and following reperfusion, 19 mongrel dogs were studied. Refractory periods were determined by the extrastimulus method in nonischemic and ischemic zones prior to and after variable periods of left anterior descending artery occlusion and reperfusion. After 15-30 minutes of occlusion, refractory periods ...
متن کاملTreatment of acute coronary occlusion.
During the past thirty years, the diagnosis of acute coronary occlusion has been greatly facilitated and its treatment has been greatly improved. The diagnosis has been improved by the routine use of 12 electrocardiographic leads and by the recognition of atypical symptoms. Numerous mild cases have, thereby, been discovered and a broader understanding of the disease has been reached. It should ...
متن کاملEffects of Acute Coronary Occlusion
To establish the effect of local and remote myocardial ischemia on interventricular septal motion, 27 open-chest dogs were studied using ultrasound and radioactive microspheres. In 14 dogs the left anterior descending coronary artery was ligated. If the ultrasound beam traversed ischemic septum (proximal LAD occlusion), significant (P < 0.05) declines in systolic septal velocity (26.4±2.9 to 6....
متن کاملOrally administered NHE1 inhibitor cariporide reduces acute responses to coronary occlusion and reperfusion.
Na+/H+exchange (NHE) mediates myocardial ischemic and reperfusion injury. We examined the effects of dietary administration of the potent and selective NHE1 inhibitor cariporide on acute responses to coronary artery ligation and reperfusion in the anesthetized rat. Male Sprague-Dawley rats received control rat chow or an identical diet containing 3 parts per million of cariporide for 1 wk befor...
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ژورنال
عنوان ژورنال: Journal of Nippon Medical School
سال: 1991
ISSN: 0048-0444,1884-0108
DOI: 10.1272/jnms1923.58.601